doxycycline hcl pharmaceutical raw material
Product Description
Item | Specification |
Characteristics | Yellow crystalline powder |
Identification | a) HPLC results b) TLC results c) Color reaction with sulfuric acid d) Color reaction with silver nitrate |
PH | 2.03.0 |
Specific optical rotation | -105-120 Deg. |
Specific absorbance at 349nm | 300-335 |
Light-absorbing impurities 490nm | 0.07 max |
Related substances | a) Methacycline: 2.0% max b) 6-epidoxycycline: 2.0% max c) 4-epidoxycycline: 0.5% max d) 4-epi-6-epidoxycycline: 0.5% max e) Oxytetracycline: 0.5% max f) 2-acetyl-2-decarbamoyldoxycycline: 0.5% max g) Any other impurity: 0.5% max h) Not indentified impurities:0.1%max |
Ethanol | 4.36.0% |
Heavy metals | 40ppm max |
Water | 1.42.8% |
Sulphate ash | 0.4% max |
Assay | 95.0%102.0% (C22H25ClN2O8) 88.0%~94.0%( C22H24N2O8) basedon anhydrous, ethanol-free substance |
Conclusion: doxycycline hcl fulfils BP2002
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Product Categories : Human API > Doxycycline Hcl
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